We Didn’t Jump On The Alcohol-Free Bandwagon … We Pioneered It!

Since 1984, Oxyfresh dental professionals just like you have turned to our proprietary and patented formulas for safe and effective dental oral care, and that’s made us a trusted industry leader. With Oxyfresh by your side, you have a proven system that gives you and your family the exceptional home care experience you need and want.

What is the Oxyfresh difference?

Oxygene® – the ultimate eliminator of odors, is a powerful, non-toxic ingredient found in Oxyfresh’s revolutionary bad breath fighting products. Nobody else has it! Oxygene is Oxyfresh’s registered name for the exclusive proprietary ingredient that safely and completely destroys odors at their source.






We Offer:

  • Clinically proven breath management
  • Tested and proven products that show remarkably low abrasion rates
  • Sodium chlorite and zinc formulas to reduce the harmful effects of VSCs
  • Xylitol to add extra caries protection and reduce biofilm plaque
  • Gentle formulas to protect tissues and preserve cosmetic dentistry
  • Fluoride and fluoride-free options
  • Sugar-free, aspartame-free and saccharine-free products
  • Drug-free, dye-free and alcohol-free products to provide safe choices for
    every age
  • Products that don’t cause a harsh burning sensation, which can be harmful to tissues
  • Safe ingredients to compliment whitening and long-term periodontal
  • Exclusivity – allows for professional guidance and instruction
  • Completely customized products for a wide range of needs


When you choose Oxyfresh, you choose a complete home care line that delivers confidence and results so you can provide quality service and care with every treatment plan.




Oxyfresh Beats Store-Brand Products In New 12-Month Study!

The exciting results are in from a 12-month, double blind clinical study published in the International Journal of Biomedical and Advance Research.

Oxyfresh toothpaste and mouthrinse went up against conventional store-brand products to see how they compared in reducing plaque and improving gum health in periodontitis patients.


The results confirm what thousands of dental professionals and loyal customers already know: Oxyfresh products truly deliver a superior home dental care experience.

Click here to download the study

From Published Article: Rajiv Saini / The Clinical and Antimicrobial Effects of Chlorine Dioxide / International Journal of Biomedical and Advance Research 2015; 6(02): 149-153.




More Science!

Oxygene® Works!
Steven J. Spindler, DDS, and Gregg A. Spindler

Evaluation of Oxyfresh Toothpaste and Rinse regimen vs. Listerine

CRA Fresh Breath Study
This study compares Oxyfresh with 18 competitors to determine what each products’ breath masking time is. See how Oxyfresh compares with brands such as Colgate, Breath RX and Rembrandt.

Evaluation of the Effects of Mouthrinses on the Hardness of Esthetic Restorative Materials
by Kevin B. Frazier, D.M.D. and John C. Wataha, Ph.D.
Mouthrinses are used to control a variety of dental conditions including gingivitis, caries, xerostomia and malodor. Previous studies have shown that alcohol-containing products can affect selected physical properties of resin-based restorative materials.
Read More: Abstract | Full

A New Anti-Halitosis Mouthrinse
by Kenneth A. Binkley, DDS, Michael J. Colvard, DDS, MS, and Michael Oester, PhD
A Pilot Study Of The Effectiveness and Substantivity Of A New Anti-Halitosis Mouthrinse.

Oral Malodor: A Periodontal Perspective (off site)
by Dr. Perry R. Klokkevold, DDS, MS
This article reviews the etiology, diagnosis and treatment of oral malodor from a periodontal perspective. The connections among periodontal pathogenic microorganisms, periodontal disease and oral malodor is probably not caused by periodontal disease, there is ample evidence to suggest that periodontal disease increases the severity of oral malodor.

Xylitol Studies and Excerpts
Xylitol: A controversial sugar substitute used in chewing gum. Xylitol is in fact a sugar alcohol obtained from birch chips. But because the body metabolizes it less completely than sucrose, limited amounts of it (no more that 60 grams a day) are considered safe for diabetics.





Plagued by Bad Breath? Chances Are Your Tongue is the Culprit
It’s probably not your diet, teeth or gums that’s causing your bad breath. Most likely, it’s your tongue. And the solution may be as simple as adding a daily tongue cleaning to your regular brushing and flossing routine.

Oxyfresh Toothpastes Are Safe, Gentle and Effective
In the wake of government warnings to avoid using toothpaste made in China because it may contain a poisonous chemical used in antifreeze, it’s comforting to know that Oxyfresh’s exclusive and proprietary dental products are made in the United States.

Oral Health: The Mouth-Body Connection
Maintaining optimum oral care can do more than give you fresh breath and a great smile. It can promote your entire physical health. Mounting research reveals a strong connection between oral health and the well-being of the rest of your body.

How to Guide Your Patients to the Products that are Right for Them (PDF)
by Rachel Wall, RDH, BS
We’ve all seen it. The poor souls lost on the dental aisle of the local discount retailer. You want to reach out to them but you’re afraid of invading their privacy. They stand there, scanning the mountain of products available, confused about what to buy. But don’t worry. There is a way you can help, a way you can make a difference and it starts with your patients.

One Size Doesn’t Fit All. Find Out Which Toothpastes Meet the Specific Needs of Your Patients (PDF)
by Rachel Wall, RDH, BS
Toothpaste is an American tradition. Staunch loyalties often determine our choice of toothpaste. I bet you can even remember the brand of toothpaste you used as a child. I know I can.

Why Clean Your Tongue (PDF)
by Gordon Christensen, DDS, MSD, PhD
The well-respected, Dr. Christensen explains how the benefits of tongue cleaning far outweigh the small investment and time required.

The One-Minute Solution: Oxyfresh Mouthrinses
Most dental companies that market products for oral malodor and prevention give you one choice when it comes to rinses. Here’s where Oxyfresh sets the standard in home care: FIVE mouthrinses each with a unique combination of ingredients that insure each patient gets what is needed for long-term hygiene support and maintenance.

Oxygene®: Oxyfresh’s Exclusive Odor Eliminator
The bad breath from that cheeseburger with extra onions you had for lunch will linger for hours – if you let it. Nobody wants bad breath, that’s why big-brand dental product companies spend millions of dollars each year trying to sell you their breath-freshening products.

Halitosis: As Seen Through the Mirror of a Wet-Fingered, Full-Time, Down-in-the-Trenches, General Dentist…Just Like You!
by Michael Rechter, DDS
I first heard of sodium chlorite while sitting in a continuing education seminar about five years ago. The lecturer was heralding the effects of this active ingredient as a very powerful oral deodorizer, which would also have some serious periodontal implications.

A Gem of a Gel
by Thomas Ventullo, DMD and Joseph S. Rubino, DMD
As a follow-up to the Oxyfresh article published in The Profitable Dentist, January 1992, and at the request of many readers, we would like to better explain some of the applications we have found for the sodium chlorite based Oxyfresh Gel in our practice.